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Plate-forme d'Exploration du métabolisme : des gènes aux métabolites





The development since fifteen years of the "omics technologies" gives biologists access to the large variety of the life components and allows them to initiate the integration of different cellular organization levels in order to propose a functional arrangement of genes and an interpretation of their reactivity relating to external variables, which define a phenotype.

With the current possibility to analyze, identify and quantify sets of tissues and biofluids metabolites, the study of metabolism (founding discipline of biochemistry) is receiving renewed attention. The metabolic phenotypes (or metabotype) resulting of hierarchical (transcription, translation) and enzymatic regulations, provide a readout of the metabolic state and is the product of genetic and environmental.

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